A microfluidic device for manufacturing lipid nanoparticles for delivering mRNA vaccines. The device is manufactured using 3D printing, which allows for routing of fluids in 3 dimensions. This opens up unique design possibilities that improve control over nanoparticle size, composition, and uniformity.
A transmission electron micrograph of lipid nanoparticles fabricated using 3D fluid routing. These nanoparticles carry an mRNA vaccine against the SARS-CoV-2 virus.